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To perceive the significance of the BPC 157 therapy and the activation of the collateral pathways [66,71,72,73,74,75,76,77,78,79,80,81,82], it should be emphasized that, without therapy, the lithium treated rats experienced severe muscular weakness, failed and congested vessels, and full occlusion-like syndromes [80]

Z.CuiY.et al (2016)

There is one small pilot study in humans (examining knee pain, where 7 of 12 participants reported sustained improvement beyond 6 months) and a 2025 safety study confirming BPC-157 was well tolerated in healthy adults